This document specifies the techniques for calibration and usage of pressurised, well-type
ionisation chambers for activity measurements of radioactive sources. Such instruments are
used to determine the activity, expressed in becquerel (Bq), of photon and some medium to
high-energy beta-emitters.

This document addresses calibration procedures of ionisation chambers and radionuclide
calibrators to be used by equipment manufacturers, national metrology institutes and
designated institutes, radionuclide producers, suppliers, distributors, and end users, like
nuclear medicine facilities, industrial or hospital (radio)pharmacies, research laboratories, and
nuclear power plants.

This document provides the methods and tests for establishing conformity of device
acceptability and maintaining acceptable instrument performance. Performance benchmarks
vary depending on the application, so information is given specific to field class instruments for
end users and reference class instruments for standards laboratories and instrument
manufacturers.

The ionisation chamber or radionuclide calibrator can be an instrument that is used as a
standalone device, but it can also be integrated in a much larger appliance, such as a laminar
air flow cabinet, a fume hood, a hot cell, or a dispensing unit. The instrument can also be
equipped with accessories that are essential for the intended use of the appliance that
surrounds and incorporates the radionuclide calibrator. The proper use of each of the
accessories can be important for the correct use of the radionuclide calibrator and therefore is
part of the scope of this document.

The software and computer system(s) that can be used to control the radionuclide calibrator
hardware and functioning are considered an integral part of the device and therefore are also
considered part of the scope of this document.

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